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Interchangeable Microscope Modules

Photonics.com
Sep 2016
Siskiyou Corp.Request Info
 
GRANTS PASS, Ore., Sept. 2, 2016 — Interchangeable Microscope ModulesSiskiyou Corp. has announced a comprehensive set of interchangeable modules and accessories that enable users to customize the functionality of optical microscopes from all major manufacturers or build their own microscope.

The heart of the system is a CBH-1.0 cube beamsplitter assembly, designed to sit in the infinity space of a conventional microscope. The CBH-1.0 provides open access in two orthogonal axes perpendicular to the microscope tube axis and forms the foundation to which a range of other optomechanical modules can be attached. These modules combine the flexibility of an open cage or breadboard microscope system with the rigidity and stability of a traditional, monolithic, tube-based microscope.

The range of modular accessories includes a self-registering slide assembly that allows a 45º beamsplitter or mirror to be smoothly inserted or removed from the microscope tube without disruption or misalignment of the optical path. This permits various filters to be used interchangeably in the excitation light and/or imaging path.

The microscope modules are ideal for applications throughout life sciences, enabling a conventional fluorescence microscope to be configured for sophisticated imaging applications without the high cost of a specialty optical instrument. In particular, they provide a simple means of combining wide-field imaging with local fluorescence excitation and probing in applications from optogenetics to photosynthesis studies.


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GLOSSARY
optogenetics
A discipline that combines optics and genetics to enable the use of light to stimulate and control cells in living tissue, typically neurons, which have been genetically modified to respond to light. Only the cells that have been modified to include light-sensitive proteins will be under control of the light. The ability to selectively target cells gives researchers precise control. Using light to control the excitation, inhibition and signaling pathways of specific cells or groups of cells...
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