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Biophotonics International presents the latest global developments and techniques in the photonics industry to those in the medical and biotechnology fields. Photonics, the science of light, has a history of success in solving clinical and research problems in diverse applications through such products and techniques as spectroscopy, lasers, microscopy, imaging and fiber optics.

Biophotonics International provides a unique source of information to the medical field because photonics products and techniques reach across various disciplines. Readers involved in cardiology, neurosurgery, pharmaceuticals and animal sciences can be reached in one magazine thanks to Biophotonics International's unique coverage of this cutting-edge science.

Each issue contains special applications features plus topical columns such as "Biophotonics in Practice," "Technology Solutions," or "Biophotonics in Research," in addition to the latest industry news, government news, information on courses, conferences, and literature, and new product listings.

For more information, or to request a copy of the latest issue, contact us at biophotonics@laurin.com .

To subscribe to Biophotonics International go to the subscription area .

 

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APRIL 2008 | CONTENTS

Features   

Raman Spectroscopy                            


Raman Spectroscopy Meets Flow
Cytometry
by Dr. John Nolan, La Jolla Bioengineering Institute
A new paradigm in spectral encoding extends the multiplexing
capabilities of flow cytometry for cell and molecular analysis.
page 30
 

Tip-Enhanced Raman Spectroscopy
for Bioanalysis

by Dr. Tanja Deckert-Gaudig, Elena Bailo and Dr. Volker Deckert,
ISAS -- Institute for Analytical Sciences
Technique combines advantages of atomic force microscopy and
Raman spectroscopy.

page 33

Raman Spectroscopy Analysis of Polymorphspg21.jpg
by Dr. Robert Alexander, PerkinElmer Ltd.
Polymorph identification is important for the pharmaceutical industry,
and Raman spectroscopy can provide a simple way to perform
this analysis.

page 35

Nanotechnology and Photonics Join Forces
in Biomedicine
by David Shenkenberg, Associate News Editor
Nanoscale antennae improve optical imaging, nanostoves speed
up DNA analysis, and nanocontainers could deliver drugs and
imaging agents.

page 38

Magnetic Resonance Imaging Moves Ahead
by Hank Hogan, Contributing Editor
New research includes assessment of capsid-based contrast
agents as well as a method to detect the early stages of
osteoarthritis.
page 42


Columns  
  pg42.jpg

Biophotonics Research 
page 48

  • Dark states of monomeric red fluorescent proteins studied
  • Doing well in the shadow of GFP
  • Molecular junction, what's your function?
  • Sea-urchin-shaped gold nanoparticles hold promise
    for bioimaging
  • Three techniques used to study the cell surface of a
    human pathogen


Post Scripts

by Nancy D. Lamontagne
Iron crystals may play a role in neurodegenerative diseases
page 84

Departments      

Editorial 
page 8

Company Index 
page 10

As We Go To Presspg48.jpg
page 12

  • Eyes provide insights into multiple sclerosis
  • GFP trapped in a nanodrop
  • Soil bacteria survive on antibiotics alone
  • Three-dimensional virus image captured with 4.5-Å resolution

Technology Solutions 
page 16

  • Genetically encoded FRET biosensors offer insight into
    disease mechanisms
  • Understanding protein crystallization

Biophotonics News  pg84.jpg
page 20

  • Imaging/biopsy system for breast cancer detection
    assessed
  • Single molecules detected using dual-colored probes
  • High-speed imaging of whiskers
  • Interactions between an elastic solid and a flowing fluid
    measured, filmed
  • Optical frequency comb spectroscopy checks breath
    for disease
  • NIR camera captures laser ablation process on teeth

From the Clinic
page 46

From the Journals
page 57

Courses & Shows
page 58 

New to the Marketonthecover.jpg
page 64 

New Media
page 81

Advertiser Index
page 83