Metabolic profiling

Bruker BioSpin Corp. has released the NMR Metabolic Profiling Database for metabolite identification and quantification. Developed collaboratively by Bruker, food and pharmaceutical companies, and universities involved with metabolomics, the resource contains information on common endogenous metabolites in such body fluids as urine, blood and cerebral spine fluid, and on known metabolites of some over-the-counter drugs and selected food components. Data for the metabolites includes measurements at a number of pH levels. Emphasis is placed on 2-D NMR experiments because of the complexity of biofluid spectra. The database interfaces with the company’s TopSpin or Amix software platforms and augments the integrated Metabolic Profiler, a system that combines NMR with time-of-flight mass spectrometry.