June 2004

Biophotonics International magazine presents the latest global developments and techniques in the photonics industry to those in the medical and biotechnology fields. For more information, or to request a copy of the latest issue, contact us at biophotonics@laurin.com .

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JUNE 2004 | CONTENTS

Features

Colorful Fluorescence Stands Out in Black and White
by Brian Matsumoto and Ken Linberg, University of California, Santa Barbara, and
Richard Crandall, Optronics
It would seem that a color digital camera would be the best choice for multicolor analysis, but a black-and-white camera can actually offer higher spatial resolution.
page 36

Positioning Issues for Inverted Microscopes
by Dave Denu, Ludl Electronic Products Ltd.
page 40

Control Technology Helps Reduce Errors
by Scott Jordan, PI (Physik Instrumente) USA
page 41

Stage Positioning Provides High-Speed Precision for 3-D Images
by Dr. William O'Brien, Mad City Labs Inc.
page 44

Positioning Offers Imaging Options
by James Hunt, Prior Scientific Inc.
page 45

Femtosecond Laser Pulses in Biology:
From Microscopy to Ablation and Micromanipulation
by Marco Arrigoni, Coherent Inc.
Until recently, biological applications for ultrafast laser pulses were confined to sample interrogation, but now the lasers also are being used for sample manipulation.
page 48

Columns

Biophotonics Research
page 52

Mirror, mirror, on the chip
Photonic nanojets break the diffraction limit
Low-cost frequency-domain fluorescence lifetime microscopy
UV resonance Raman spectroscopy discriminates between bacteria species
Bridging the resolution gap
Dark-field illumination sheds light on chemotaxis

Post Scripts
by Karen E. Greb
Reconstructing Tyrannosaurus rex
page 86

Departments

Editorial
page 9

Manipulating memories

Company Index
page 13

As We Go To Press
page 14

Multiphoton polymerization resin displays biocompatibility
CT may aid cancer treatment
UV radiation helps arrest culprits in graft-vs.-host disease

Technology Solutions
page 16

Cuvette-free spectrophotometer measures very small samples
Piezo technique improves survival rates in nuclear transfer
Spaceborne rain gauge monitors drought effects

Biophotonics News
page 22

Force microscopy images interactions of optically trapped particles
Investigating ambient light for color signal evolution
NIST develops scale for fluorescence measurement
OCT compares favorably with clinical diagnosis of diabetic macular edema
Reading time is longer for digital mammograms than for film
Alternative to PCR detects anthrax with high sensitivity
Real-time video of cells uncovers unusual mitochondrial changes
Eye surgery outcome affected by environment

Government Matters
page 34

From the Clinic
page 62

Courses & Shows
page 63

Business Digest
page 67

New to the Market
page 68

New Media
page 83

Advertiser Index
page 84