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Controlled Switching of GFP Suggests Applications in Optical Data Storage

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Gary Boas

Researchers have devoted a great deal of effort to probing the photophysical and photochemical properties of green fluorescent protein (GFP). Many are especially interested in the transitions between GFP's fluorescent and nonfluorescent (bright and dark) states that reversibly and quickly turn it on and off (known as blinking or flickering) and lead to photobleaching. Control of these transitions could open the door to a number of new applications of GFP. Recent studies have demonstrated that irradiation with blue/UV radiation may enable the recovery of fluorescence emission after...Read full article

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    Published: January 2005
    Glossary
    photochemical
    The term photochemical pertains to chemical processes or reactions that are initiated or influenced by the absorption of light. Photochemical reactions involve the interaction of light, often in the form of ultraviolet or visible radiation, with molecules, leading to changes in their chemical structure or properties. These reactions are distinct from thermal or non-light-induced chemical reactions. Key characteristics of photochemical reactions include: Light absorption: Photochemical...
    fluorescentgreen fluorescent proteinMicroscopynonfluorescentphotochemicalphotophysicalResearch & Technology

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