CONFOCAL MICROSCOPE

A microscopy method developed at the University of Freiburg is able to resolve cellular-level detail without fluorescence, enabling observations 100 to 1000× longer and 10 to 100× times...

Using image-based flow cytometry, researchers at the Technical University of Munich (TUM) identified a biomarker for predicting how serious a COVID-19 infection will be. They also developed a rapid...

Superresolution radial fluctuations (SRRF), a superresolution algorithm, works by observing fluctuations in radial symmetry throughout the frames of an image. SRRF supports live-cell, superresolution...

Therapy-induced senescent (TIS) cells are cancer cells that become resistant to therapies and enter a dormant stage. These cells can emerge from dormancy and induce tumor resistance and relapse. To...

Mix-n-Stain™ CF® Dye IgM Antibody Labeling Kits from Biotium offer efficient and convenient conjugation with bright CF dyes. The kits allow researchers to easily obtain...

Rapid Automated Modular Microscope is mounted on the RAMM frame that supports the microscope assembly and the stage in a manner that ensures close coupling between sample and objective to minimize...

The DAG20-120-01 and the DAG20-120-04 motorized elevator stages from Optimal Engineering Systems Inc. are high-resolution, compact, low-profile devices with high-stability 120- × 120-mm tables...

Compact piezo lens nanopositioners with closed-loop control and travel ranges up to 200 μm. Designed to hold and move objective lenses with very low off-axis motion and subnanometer precision. The...

NSOM is suitable for studies on the mesoscopic scale (several tens to hundreds of molecular dimensions). It has become an important tool in research and applications of semiconductors, organic layers...

As recently as five years ago, shopping for a microscope light source was fairly straightforward. For routine applications, it was tungsten halogen, typically 100 W, while for fluorescence, it was an...

Laser development for the microscopy market continues to be driven by key trends in applications, which currently include superresolution techniques, multiphoton applications in optogenetics and...

By its original definition, a nanopositioning device is a mechanism capable of repeatedly delivering motion in increments as small as one nanometer. Lately demands from industry and research have...

This whitepaper looks at the unique challenges associated with optical systems by exploring two extremes, an ultra-high precision instrument, and a low-cost consumer product, and the different...

The Laser Line Tunable Filter (LLTF) is a non-dispersive, widely tunable bandpass optical filter. At its core lies a volume Bragg grating (VBG) which efficiently selects and filters all but a narrow...

Raman microscopy is an ideal method for analysing gemstones and other geological samples. Its non-destructive nature and lack of sample preparation make it particularly advantageous for analysing all...

Many factors affect the price of confocal microscopy systems and when purchasing a microscope, one must consider the complexity of the instrumentation and the capabilities it provides. Clearly the...

Success in a specific market depends on meeting the right technical requirements. As demand increases, it becomes necessary to develop and establish new manufacturing processes to produce functional...

The size and number of images for image acquisition instruments and processing techniques have grown exponentially, along with the associated storage needs and network requirements. In the fields...

Join Photonics Media online Oct. 24-26 for the BioPhotonics Conference, a virtual event highlighting innovation in the life sciences and biomedical optics. The conference will feature three keynotes...

Matrix-assisted laser desorption/ionization (MALDI) imaging is a powerful mass spectrometry-based approach that allows for the simultaneous detection of hundreds of biomolecules from one tissue...

Light produced by visible radiation that moves from the light source to the object without reflection. With respect to microscopy, this is the light that directly strikes the stage of the microscope...

The Shack-Hartmann wavefront sensor is an optical device used for measuring the wavefront aberrations of an optical system. It is widely used in adaptive optics systems to correct distortions and...

Label-free refers to a technique or method that does not require the use of additional labels, tags, or markers to detect or identify specific components or entities. In various scientific and...

A metalens, short for "metasurface lens," is a type of optical lens that uses nanostructured materials to manipulate light at a subwavelength scale. Unlike traditional lenses made of glass or other...

This Software Highlight focuses on Fast Mapping in our Ramacle software. Fast Mapping enables the user to acquire Raman maps with significantly reduced acquisition times via more efficient stage...

This hands-on session about FD-FLIM by Gerhard Holst from PCO AG was given as part of the FLIM Symposium "Beginners Guide to Fluorescence Lifetime Imaging in Life Sciences".

Established in 1990, Applied Scientific Instrumentation is a reknown American company committed to the advancement of science. ASI products have been thoroughly tested and evaluated in numerous labs...

The Dragonfly 600 confocal microscope system delivers outstanding multi-dimensional images from subcellular (nm) to whole organism (cm), while significantly boosting productivity. Its unrivalled...

A petrographic microscope is a microscope equipped with a polarizer, an analyzer and a Bertrand lens to focus on the upper focal plane of the objective. It is used chiefly by mineralogists and...

A scanning tunneling microscope is a high-resolution imaging instrument that can detect and measure the positions of individual atoms on the surface of a material. A very fine conductive probe is...

Andor Technology Ltd is a global developer and manufacturer of high-performance scientific cameras, microscopy systems and spectrographs for academic, government, and industrial applications. Founded...

Photron has been a global market leader in high-end, high-speed camera systems for over forty years. The company’s continuing development of new state-of-the-art products illustrates a...

For over 30 years, Allied Vision has helped people see the bigger picture to achieve their goals. We believe knowledge is power and always strive to deliver valuable insight with our technology...

For over 100 years, Prior Scientific has been manufacturing precision optical and electro-mechanical equipment and instrumentation. Prior is a leader in the development of precision motion,...