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CARS flow cytometry on a chip

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Sensitive technique offers alternative to fluorescent labeling.

Kevin Robinson

Researchers at Purdue University in West Lafayette, Ind., have developed a flow cytometer that relies on a microfluidic chip and coherent anti-Stokes Raman scattering (CARS). Although in its early stages, their work offers the potential of the increased sensitivity of the CARS signal as well as the small sample size and versatility of microfluidics. Flow cytometers are one of the mainstays of chemical analysis. They can analyze thousands of cells or other analytes rapidly and then sort them based on the analysis. They typically are used to tag a target cell with a fluorescent label. Then,...Read full article

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    Published: June 2008
    BiophotonicsCARS signalflow cytometerindustrialmicrofluidic chipMicroscopyResearch & TechnologySensors & Detectors

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