An addition to the “Subcellular Biochemistry” series, the book Subcellular Proteomics: From Cell Deconstruction to System Reconstruction describes the various levels of subcellular organization and their methodologies. Written by experts in the field, the 412-page publication addresses membrane proteomics, organelle subproteomes and the characterization of supramolecular protein complexes. A section on systems biology deals with the integration of the data derived from the various levels to produce a synthetic description of the cell as a system. A survey of advanced technical developments in proteomics covers single-cell analysis methods, molecular imaging and liquid-chromatography matrix-assisted laser desorption/ionization. Eric Bertrand and Michel Faupel, eds; !%Springer%!, New York, 2007; $239.