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Gold nanorods align to reveal cancer cells’ locations

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Michael J. Lander

For targeting and revealing cancer cells, gold nanorods bound to antibodies may provide a useful tool. Led by Mostafa A. El-Sayed of Georgia Institute of Technology in Atlanta, researchers from this institution and from the University of California, San Francisco, have used the gold nanostructures to yield distinct spectroscopic signals from cancer cells. Their method could find application in diagnosis of the disease. The scientists applied the concept of surface-enhanced Raman spectroscopy, in which the surfaces of nanoscale metal particles are used to increase the Raman signal of...Read full article

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    Published: July 2007
    Glossary
    surface-enhanced raman spectroscopy
    Surface-enhanced Raman spectroscopy (SERS) is an analytical technique that combines the principles of Raman spectroscopy with the enhancement provided by nanostructured metallic surfaces. Raman spectroscopy is a method used to study vibrational, rotational, and other low-frequency modes in a system by measuring the inelastic scattering of monochromatic light, typically from a laser source. SERS enhances the Raman signal by many orders of magnitude, enabling the detection and identification of...
    BiophotonicscellsMicroscopynanoscaleResearch & Technologyspectroscopysurface-enhanced Raman spectroscopy

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