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Induced viral gene expression used to image tumors

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Michael J. Lander

Studies have shown that certain cancers may be caused by viruses that infect and alter cells. Recently, scientists from Johns Hopkins Medical Institutions developed a technique for imaging the expression of viral genes in those cancers. In contrast to other techniques for molecular-genetic imaging, their method does not require transfection of the target cells. In developing the method, Dr. Martin G. Pomper, Dr. Richard F. Ambinder and colleagues concentrated on the thymidine kinase gene found in tumor-associated gamma herpes viruses such as Epstein-Barr. They knew that, when in the...Read full article

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    Published: April 2007
    BiophotonicscellsImagingJohns Hopkins Medical InstitutionsNews & Features

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