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Gadolinium-based MRI contrast agents and a rare condition

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Research has revealed an association between the commonly used gadolinium-based MRI contrast agents and a rare disease called nephrogenic systemic fibrosis. The vast majority of the cases have occurred in patients with severe or end-stage kidney disease. Approximately 90 percent were on renal dialysis. Nephrogenic systemic fibrosis is an emerging disorder characterized by an increase of collagen in the tissues, causing thickening and hardening of the skin of the extremities and sometimes involving other tissues. Within weeks after onset, patients may require a wheelchair. Although...Read full article

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    Published: February 2007
    As We Go To PressBiophotonicsBreaking Newsgadolinium-based MRI contrast agentsnephrogenic systemic fibrosisPresstime Bulletintissues

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