An addition to the Experimenter Series, the fourth edition of Molecular Biology and Genomics includes sections on minisequencing, pyrosequencing and RNA-interference, as well as a brief introduction for younger researchers on career planning. The 266-page laboratory guide explores the methodologies in the field, discussing their advantages, drawbacks and critical points. Providing suggestions for more successful experiments, it summarizes routine procedures and details aspects of alternative methods. Suitable for laboratory practitioners such as professionals, managerial staff, instructors and students, the book presents methods such as those for DNA preparation and the purification of nucleic acids, along with tools including gels, blotting and restriction enzymes. Sections address the polymerase chain reaction, DNA fragment cloning and the production of labeled probes. References and an index are provided. Cornel Mülhardt; Academic Press, an imprint of Elsevier, Burlington, Mass., 2007; $44.95.