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NIR spectroscopy to predict pill quality

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Laura S. Marshall, [email protected]

The quality-testing process for pharmaceuticals raises drug costs, according to pharmacy professor Stephen Hoag, but he says that evaluation with near-infrared spectroscopy could help lower those costs. “The drug industry used to test a pill for dissolution, then send a sample for analysis to a wet lab,” said Hoag, who works at the University of Maryland School of Pharmacy. “Now – with near-infrared high-speed computers and software – you can get information in real time. So instead of evaluating each step and waiting three days for samples to come back, [testing] is instant. “It...Read full article

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    Published: February 2010
    Glossary
    near-infrared spectroscopy
    Near-infrared spectroscopy (NIRS) is a non-invasive analytical technique that uses the near-infrared region of the electromagnetic spectrum to study the absorption of light by molecules in a sample. This technique is commonly applied in fields such as chemistry, biology, medicine, and agriculture for qualitative and quantitative analysis of various substances. Key features and principles of near-infrared spectroscopy include: Near-infrared region: NIRS typically covers the spectral range...
    coated tabletsconsumer drugscontrolled-release tabletdissolutiondrug regulationsdrugsFDAhealth careImagingindustrialInternational Journal of Pharmaceuticsmedicationnear-infrared spectroscopyNIRpharmaceuticalspharmacyphysical polymerspillsprescriptionqualityquality measurementResearch & TechnologyspectroscopyStephen HoagTech PulsethiophyllineUniversity of Maryland School of Pharmacywet lab

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