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Strathclyde Institute of Pharmacy and Biomedical Sciences

Jul 2010
At the Centre for Biophotonics of the Strathclyde Institute of Pharmacy and Biomedical Sciences, a new microscope has been built that could provide breakthroughs for cancer treatment and drug discovery. The microscope uses a less complex laser system than has previously been available for obtaining crucial detailed images of cells, tissues and drugs. The instrument will remove the need to add the toxic fluorescent labeling normally required to see specific areas of interest within the material.

The emission of light or other electromagnetic radiation of longer wavelengths by a substance as a result of the absorption of some other radiation of shorter wavelengths, provided the emission continues only as long as the stimulus producing it is maintained. In other words, fluorescence is the luminescence that persists for less than about 10-8 s after excitation.
An instrument consisting essentially of a tube 160 mm long, with an objective lens at the distant end and an eyepiece at the near end. The objective forms a real aerial image of the object in the focal plane of the eyepiece where it is observed by the eye. The overall magnifying power is equal to the linear magnification of the objective multiplied by the magnifying power of the eyepiece. The eyepiece can be replaced by a film to photograph the primary image, or a positive or negative relay...
BiophotonicsBusinesscancercancer treatmentcellsCentre for Biophotonicsdrug discoverydrugsfluorescencefluorescentimagesimaginglabelinglasersmicroscopeMicroscopyopticsRapidScanStrathclyde Institute of Pharmacy and Biomedical Sciencestissuestoxic fluorescent labeling

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