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Single-cell elasticity measured by atomic force microscopy

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Lauren I. Rugani

The effect of external forces on living cells holds importance in areas of study such as tissue engineering and cancer research. Forces induce biological transformations on the cell that can alter functionality or mechanical behavior. Two techniques that were combined and utilized to study these transformations, atomic force microscopy and confocal optical microscopy, each have disadvantages when used alone. However, when used together, they are sensitive to biological properties and structural changes and enable the investigation of single-cell mechanics. A single cell is exposed to...Read full article

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    Published: September 2006
    Basic ScienceBiophotonicsBusinessMicroscopyRapidScanSensors & Detectors

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