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World’s fastest camera takes on biosensing

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A new ultrafast camera will have applications in biological processes as well as automotive collisions and astronomical observations. The Megaframe Imager can record images at 1 million fps, far faster than the normal video rate of 24 fps. But thanks to a single-photon avalanche diode device and bespoke on-chip intelligence, higher-than-video speeds are achievable, which opens up a new range of previously unthinkable applications, from cellular and subcellular imaging to neural imaging, from biochemical sensors and DNA/protein microarray scanning, to automotive collision studies and even...Read full article

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    Published: February 2011
    Glossary
    fluorescence lifetime imaging
    Fluorescence lifetime imaging (FLIM) is an advanced imaging technique that provides information about the lifetime of fluorescence emissions from fluorophores within a sample. Unlike traditional fluorescence imaging, which relies on the intensity of emitted light, FLIM focuses on the time a fluorophore remains in its excited state before returning to the ground state. This fluorescence lifetime is influenced by the local environment and can be used for various applications in biological and...
    single-photon avalanche diode
    A single-photon avalanche diode (SPAD) is a specialized type of photodetector designed to detect extremely weak optical signals, down to the level of single photons. SPADs are widely used in applications such as quantum optics, lidar (light detection and ranging), fluorescence lifetime imaging microscopy (FLIM), and other low-light-level applications where the detection of individual photons is essential. Key features and principles of SPADs include: Single-photon sensitivity: The primary...
    astronomical observationsautomobile accidentsautomotive collisionsBiomedical Optics ExpressBiophotonicsBioScanbiosensingcamerascellular imagingEuropefluorescence lifetime imagingImagingMegaframe ImagerNational Physical Laboratoryneural imagingNewsOptical Society of AmericaOSASensors & Detectorssingle-photon avalanche diodeST Microelectronicssubcellular imagingTU DelftUKultrafast cameraUniversity of Edinburgh

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