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Nikon Instruments Inc.

BioPhotonics
Mar 2011
Nikon Instruments Inc. of Melville, N.Y., and Agilent Technologies of Santa Clara, Calif., have announced an agreement for distribution in the Americas of Agilent’s MLC400 monolithic laser combiner systems. They will be integrated into laser systems designed for Nikon’s Ti-E PFS “Perfect Focus,” an inverted research microscope that performs multiday live-cell imaging experiments. The integration will allow researchers to maximize productivity and minimize system downtime. Agilent’s monolithic laser combiner will achieve high optical efficiency on the microscopes by eliminating the need for multiple mechanical mounts on fixtures, as well as the number of exposed optical faces and air gaps. The company will begin integrating the MLC400/Ti-E imaging systems for total internal reflection fluorescence, photobleaching/ photoactivation, and field scanning confocal systems.


GLOSSARY
photobleaching
A process that helps optical fibers recover from damage induced by radiation. When silica is irradiated, bonds break and attenuation increases. Light in the fiber assists in recombining the species released by the broken bonds, decreasing attenuation.
Agilent TechnologiesbiophotonicsBusinessCaliforniaconfocal microscopyimaginginverted research microscopelaserslive-cell imagingMicroscopyMLC400 monolithic laser combiner systemsNew YorkNikon InstrumentsopticsphotoactivationphotobleachingRapidScanTi-E PFS Perfect Focustotal internal reflection fluorescence

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