!%Carl Zeiss%! of Jena, Germany, has received a license from the University of California, San Francisco, for the commercialization of multidirectional selective plane illumination microscopy (mSPIM), an advanced technique for light-sheet fluorescence microscopy. A relatively new application, light-sheet fluorescence microscopy is suitable for live imaging of fluorescently labeled specimens up to millimeters in size. Specimens can be imaged for days under certain physiological conditions and with minimum photodamage. The agreement grants Carl Zeiss the right to integrate mSPIM technology with its existing and future microscopy systems.