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PI Physik Instrumente - Revolution In Photonics Align LW LB 3/24

3-D Microscopy Goes Deeper and Deeper

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Marie Freebody, Contributing Editor, [email protected]

New systems take researchers inside the workings of tissue, cells, organelles The biomedical industry is constantly involved in biological research and development, not only examining the basic functions of cells and tissues to find targets for therapeutic intervention, but also testing new and existing drugs. Microscopy has been an essential tool for the pharmaceutical industry for many years, helping to visualize the action of drugs on tissue, cells and cellular organelles. Most light microscopes see a very thin, two-dimensional slice of a specimen, leaving the foreground and...Read full article

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    Published: February 2012
    Glossary
    nano
    An SI prefix meaning one billionth (10-9). Nano can also be used to indicate the study of atoms, molecules and other structures and particles on the nanometer scale. Nano-optics (also referred to as nanophotonics), for example, is the study of how light and light-matter interactions behave on the nanometer scale. See nanophotonics.
    superresolution
    Superresolution refers to the enhancement or improvement of the spatial resolution beyond the conventional limits imposed by the diffraction of light. In the context of imaging, it is a set of techniques and algorithms that aim to achieve higher resolution images than what is traditionally possible using standard imaging systems. In conventional optical microscopy, the resolution is limited by the diffraction of light, a phenomenon described by Ernst Abbe's diffraction limit. This limit sets a...
    3D microscopyAndorBasic ScienceBiophotonicscamerasFeaturesImaginglight microscopesMicroscopymultiphoton microscopynanoOlympus America Inc.pharmaceuticalRiken Brain Science InstituteScale View systemSensors & Detectorssuperresolution

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