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A Start on Parts for Multiphoton Microscopy

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Daniel C. McCarthy, Senior News Editor

Ten years ago, in a Cornell University laboratory in Ithaca, N.Y., researchers unveiled the first multiphoton microscope for biological imaging. The biomedical research community quickly realized the virtue of the technology, which demonstrated that two photons are better than one for maintaining cell or tissue viability during imaging. The multiphoton microscope borrowed from confocal laser scanning devices in its application of laser light to excite fluorescence in a sample, but two significant differences distinguished it from confocal techniques. First, multiphoton fluorescence is...Read full article

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    Published: November 1999
    FeaturesMicroscopySensors & Detectors

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