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Rocky Mountain Instruments - Infrared Optics LB

Laser-based testing helps detect metastasis

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Ashley N. Rice, [email protected]

A tissue-penetrating, laser-light-enhanced microscope accurately analyzes distinctive patterns of ultrathin collagen fibers in breast tumor tissue samples, which could help detect cancer’s spread. The Johns Hopkins University technique uses crisscrossing optical images, made by shining a laser back and forth across a biopsied tissue sample a few microns thick, to measure minute changes in tumor connective tissue fibers. It could potentially be used with other tests to more accurately determine the need for lymph node biopsy and removal in women at risk of metastatic breast cancer....Read full article

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    Published: January 2013
    Glossary
    microscope
    An instrument consisting essentially of a tube 160 mm long, with an objective lens at the distant end and an eyepiece at the near end. The objective forms a real aerial image of the object in the focal plane of the eyepiece where it is observed by the eye. The overall magnifying power is equal to the linear magnification of the objective multiplied by the magnifying power of the eyepiece. The eyepiece can be replaced by a film to photograph the primary image, or a positive or negative relay...
    AmericasBiophotonicsBioScanbreast cancerbreast tumorCancer Cellscollagen fibersdetection of cancer spreadingImagingJohns Hopkins UniversityKristine Glundelymph node biopsylymph nodesmetastatic breast cancermicroscopeMicroscopyNewsoptical imagingOpticssecond harmonic generation microscopytumor growthZaver BhujwallaLasers

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