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In Vivo Raman Technique Quickly Pinpoints Cholesterol

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A new high-speed spectroscopy technique that can pinpoint where cells store cholesterol could be used to study obesity and diabetes. Researchers at Purdue University used hyperspectral-stimulated Raman-scattering microscopy to map lipid metabolism in living C. elegans roundworms. Ordinarily, cells have to be processed before they can be analyzed, which rules out studying living cells. Meanwhile, conventional Raman microscopes may take hours to get results. But the new method can be used on living specimens and works at high speed, enabling researchers to measure changes in real...Read full article

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    Published: September 2014
    Glossary
    hyperspectral imaging
    Hyperspectral imaging is an advanced imaging technique that captures and processes information from across the electromagnetic spectrum. Unlike traditional imaging systems that record only a few spectral bands (such as red, green, and blue in visible light), hyperspectral imaging collects data in numerous contiguous bands, covering a wide range of wavelengths. This extended spectral coverage enables detailed analysis and characterization of materials based on their spectral signatures. Key...
    AmericasBiophotonicshyperspectral imagingIndianaJi-Xin ChengLasersMicroscopyPurdue UniversityResearch & TechnologySRSStimulated Raman scatteringHeidi A. TissenbaumBioScan

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