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Comparing Micromanipulators for Electrophysiology

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John Wingerd, Siskiyou Corporation

Several different technologies offer a range of performance options within the confines of an optical microscope for patch-clamp studies, intracellular recording and other demanding experiments in electrophysiology. Electrophysiology encompasses the measurement and analysis of transient ion flows and resultant voltage changes across cellular membranes (e.g., sodium ion channels that enable nerve-cell signal transmission). A key but often unheralded component of these experiments is the micromanipulation system used by the researcher to maneuver the micropipettes or other...Read full article

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    Published: April 2015
    Glossary
    nano
    An SI prefix meaning one billionth (10-9). Nano can also be used to indicate the study of atoms, molecules and other structures and particles on the nanometer scale. Nano-optics (also referred to as nanophotonics), for example, is the study of how light and light-matter interactions behave on the nanometer scale. See nanophotonics.
    positioning
    Positioning generally refers to the determination or identification of the location or placement of an object, person, or entity in a specific space or relative to a reference point. The term is used in various contexts, and the methods for positioning can vary depending on the application. Key aspects of positioning include: Spatial coordinates: Positioning often involves expressing the location of an object in terms of spatial coordinates. These coordinates may include dimensions such as...
    FeaturesnanoBiophotonicsMicroscopypositioningAmericaselectrophysiologymicromanipulatorsion flowscellular membranessodium ion channelspatch clampmembraneAndrew HuxleyHuxley flexuresmechanical micromanipulatorsMX300 seriesMX7600 systemMX6000 seriesSiskiyou Corp.John Wingerd

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