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Third-Harmonic Generation Microscopy Images Brain Tumors In Situ

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A technique involving third-harmonic generation microscopy could allow neurosurgeons to image and assess brain tumor boundaries during surgery, providing optical biopsies in near-real time and increasing the accuracy of tissue removal. Pathologists typically use staining methods, in which chemicals like hematoxylin and eosin turn different tissue components blue and red, revealing its structure and whether there are any tumor cells. A definitive diagnosis can take up to 24 hours, meaning surgeons may not realize some cancerous tissue has escaped from their attention until after surgery...Read full article

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    Published: April 2016
    Research & TechnologyeducationEuropeAmsterdamNetherlandsmarloes grootBiophotonicsMicroscopycancerneuroImagingthird harmonic generationMicroscopy Special Section

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