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Microscopy Method Enables Simultaneous Imaging of 24 Molecules

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A novel microscopy platform with enhanced detection sensitivity could allow for more comprehensive, system-wide labeling and imaging of greater numbers of biomolecules in living cells and tissues than is currently possible. The platform, called electronic pre-resonance stimulated Raman scattering (epr-SRS) microscopy, offers high levels of sensitivity and selectivity. The study, performed by a research team at Columbia University, also details the creation of new molecules that, when paired with the team’s novel microscopy method, allow for the simultaneous labeling and imaging of...Read full article

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    Published: April 2017
    Glossary
    fluorescence
    Fluorescence is a type of luminescence, which is the emission of light by a substance that has absorbed light or other electromagnetic radiation. Specifically, fluorescence involves the absorption of light at one wavelength and the subsequent re-emission of light at a longer wavelength. The emitted light occurs almost instantaneously and ceases when the excitation light source is removed. Key characteristics of fluorescence include: Excitation and emission wavelengths: Fluorescent materials...
    Research & TechnologyeducationAmericasImagingMicroscopyOpticsRamanfluorescenceepr-SRS micrscopyBioScanBiophotonics

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