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Plant Protein Powers Red Light-Activated Switch for Animal Cells

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An optogenetic switch activated by red and far-red light has been designed and tested in animal cells. The light-activated switch, which does not require the addition of sensing molecules from outside the cells, could be used to turn genes on and off in gene therapies; to turn off gene expression in future cancer therapies; and to help track and understand gene function in specific locations in the human body. Researchers from the University of California San Diego, Quinnipiac University, and the University of Iowa devised a way to enable animal cells to transfer enough electrons from...Read full article

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    Published: April 2018
    Glossary
    optogenetics
    A discipline that combines optics and genetics to enable the use of light to stimulate and control cells in living tissue, typically neurons, which have been genetically modified to respond to light. Only the cells that have been modified to include light-sensitive proteins will be under control of the light. The ability to selectively target cells gives researchers precise control. Using light to control the excitation, inhibition and signaling pathways of specific cells or groups of...
    Research & TechnologyAmericaseducationLight SourcesOpticsoptogeneticscancermedicalBiophotonicsPhyB optogeneticsred lightlight-activatedfar red lightBioScan

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