Raman spectroscopy has emerged as an important tool in determining analytical and structural information concerning low concentration aqueous biomolecules. However, many samples require in vivo or in situ sampling.
To solve this problem, scientists from the University of British Columbia in Vancouver, Canada, have developed high-performance probes suitable for long-term use in pulsed UV resonance Raman spectroscopy.
The probes incorporate UV fibers that do not exhibit the rapid solarization and decay that plagued previous types of probes.
Using the new fibers, the research team obtained data at wavelengths shorter than 250 nm, and achieved increased efficiencies and high-
energy throughputs.