Search Menu
Photonics Media Photonics Marketplace Photonics Spectra BioPhotonics Vision Spectra Photonics Showcase Photonics ProdSpec Photonics Handbook

Imaging System Offers Clearer Tissue Visualization

Facebook Twitter LinkedIn Email
WALTHAM, Mass., March 5, 2014 — Studying proteins and disease markers could get easier, thanks to a new high-throughput imaging system called Lamina.

A team at PerkinElmer Inc. designed the multilabel slide scanner to enable research pathologists to more easily analyze protein expression and the relationships between disease markers in formalin-fixed, paraffin-embedded (FFPE) tissue sections.

The device will provide a more comprehensive understanding of diseases for the development of more effective treatment and therapy, the researchers say.

A new high-throughput imaging system will make studying proteins and disease markers easier. Courtesy of PerkinElmer Inc.

This new system will offer improvements in real time during whole-slide scanning, which also enables clearer visualization of fluorescently labeled tissues. Users will be able to obtain more accurate information from histological specimens.

“The Lamina scanner can help research pathologists more effectively interpret their images by automating work flows and providing clearer and faster results,” said Jim Corbett, president of Diagnostics, Life Sciences & Technology at PerkinElmer. “These advanced digital pathology capabilities can help lead to a better understanding of disease.”

The system reduces interference from autofluorescence, an unwanted byproduct of tissue fixation, as well as fluorophore crosstalk, in which the signal from one fluorophore bleeds into multiple channels. Both of these effects obscure real signals, which can result in an incorrect assessment of a slide.

The scanner produces digital, whole-slide images of hematoxylin and eosin, immunohistochemistry, and immunofluorescence-labeled tissue sections and tissue microarrays.

For more information, visit
Mar 2014
Material that emits fluorescence.
The technique that uses light to detect and analyze the antibodies produced by a specimen stained with an organic dye.
Immunohistochemistry (IHC) is a method for detecting antigens or haptens in cells of a tissue section by using labeled antibodies to bind specifically to their antigens. IHC is used for disease diagnosis, biological research and in drug development. Using IHC visualized tumor markers such as enzymes, oncogenes and tumor-specific antigens, physicians can diagnose if a tumor is benign or malignant and determine the stage and grade of a cancer.
1. A device used to trace out an object and build up an image. One of the most common of these types is video scanning. The scanning takes place inside the television tube as electrons, guided by electron optics, sweep linearly across a tube face coated on the inside with a phosphorescent material. A scanner can convert a paper drawing or photograph into pixels on a display screen. Scanners are also used to relay information in optical data processing. 2. A device that automatically measures or...
AmericasautofluorescenceBiophotonicsBusinesseosinFFPEfluorophorehematoxylinimagingimmunofluorescenceimmunohistochemistryLaminaMassachusettsPerkinElmerproteinsscannertissueImaging & Sensingdisease markersformalin fixed paraffin embedded tissue sections

back to top
Facebook Twitter Instagram LinkedIn YouTube RSS
©2023 Photonics Media, 100 West St., Pittsfield, MA, 01201 USA, [email protected]

Photonics Media, Laurin Publishing
x We deliver – right to your inbox. Subscribe FREE to our newsletters.
We use cookies to improve user experience and analyze our website traffic as stated in our Privacy Policy. By using this website, you agree to the use of cookies unless you have disabled them.