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3-D imaging draws new picture of Golgi during cell division

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Resolving a fundamental question in cell biology and showing off the powers of new high-resolution 3-D imaging, National Institutes of Health (NIH) scientists have discovered where the Golgi apparatus, which sorts newly synthesized proteins for transport inside and outside the cell, goes when it disassembles during cell division, according to research presented at the American Society for Cell Biology annual meeting in New Orleans. Conventional microscopy techniques only allow biologists to watch as the Golgi dissolve into tiny “puncta” and an unresolvable haze. But powerful...Read full article

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    Published: March 2014
    Glossary
    cell
    1. A single unit in a device for changing radiant energy to electrical energy or for controlling current flow in a circuit. 2. A single unit in a device whose resistance varies with radiant energy. 3. A single unit of a battery, primary or secondary, for converting chemical energy into electrical energy. 4. A simple unit of storage in a computer. 5. A limited region of space. 6. Part of a lens barrel holding one or more lenses.
    haze
    An aggravated form of fog in a polished surface caused by the scattering of light. The defects causing haze are larger than those causing fog, but singly are not large enough to be seen by the unaided eye.
    3-DAmerican Society for Cell BiologyAmericasassayBethesdabiologyBiophotonicsBioScanCellcisternaedivisionendoplasmic reticulumenzymeerhazehigh-resolutionImagingMarylandmembraneMicroscopymitosisNational Institute of Child Health and Human DevelopmentNational Institutes of HealthNew OrleansNIHorganellesprocessproteinsscientistsstructuretransporttrappingtubularGolgiapparatussynthesizedpunctaDylan BurnettePrabuddha SenguptaJennifer Lippincott-SchwartzEunice Kennedy ShriverNICHDchoreographeddisassemblycytokinesispharmacologically

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