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AFM Measures Mechanical Properties of Living Cells

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WEST LAFAYETTE, Ind., Nov. 22, 2011 — A new atomic force microscope (AFM) technique that measures the mechanical properties of living cells could be used to diagnose human disease and better understand biological processes. Researchers from Purdue University and the University of Oxford have used the technique to study three distinctly different types of cells to demonstrate the method’s potentially broad applications. Their paper, titled “Mapping Nanomechanical Properties of Live Cells Using Multi-harmonic Atomic Force Microscopy,” has been posted online in Nature Nanotechnology and will appear in...Read full article

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    Published: November 2011
    Glossary
    atomic force microscope
    An atomic force microscope (AFM) is a high-resolution imaging and measurement instrument used in nanotechnology, materials science, and biology. It is a type of scanning probe microscope that operates by scanning a sharp tip (usually a few nanometers in diameter) over the surface of a sample at a very close distance. The tip interacts with the sample's surface forces, providing detailed information about the sample's topography and properties at the nanoscale. Key features and principles of...
    nano
    An SI prefix meaning one billionth (10-9). Nano can also be used to indicate the study of atoms, molecules and other structures and particles on the nanometer scale. Nano-optics (also referred to as nanophotonics), for example, is the study of how light and light-matter interactions behave on the nanometer scale. See nanophotonics.
    AFMAFM techniqueAmericasArvind Ramanatomic force microscopeatomic force microscope techniqueBasic Sciencebiochemical assaysBiophotonicscellular structuresEnglandEuropeimaging biological processesIndianalive cell imagingmechanical properties of living cellsmechanobiology-based assayMicroscopymultiharmonic atomic force microscopynanonanomechanical properties of living cellsNature NanotechnologyPurdue Universityquasi-static atomic force microscopyResearch & TechnologySonia Conterasurface elastic responseUniversity of Oxford

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