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Active Substance Optically Manipulates Component of Cytoskeleton

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An international research team from Jena, Munich, and New York has used photopharmacology — the use of light to switch the effect of drugs on and off — to control actin, a component of cells that was previously considered inaccessible. “Up to now, there were no drugs available that targeted actin, because the protein is found everywhere in the body,” professor Hans-Dieter Arndt of Friedrich Schiller University said. “Such a substance would therefore have little to no targeted effect. However, our new compounds only exert activity on actin in areas where...Read full article

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