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Adaptive Optics Improves Multiphoton Imaging

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Daniel S. Burgess, Senior Editor

In the years since Bio-Rad Laboratories Ltd. of Hemel Hempstead, UK, licensed the right to commercialize multiphoton microscopy systems from Cornell University in Ithaca, N.Y., turnkey multiphoton workstations have appeared in labs worldwide. Researchers in Scotland are using adaptive optics to improve the performance of multiphoton microscopes for biological imaging, offering a glimpse of what future versions of the instruments might look like. Multiphoton microscopy, developed in 1989 by Winfried Denk, James P. Strickler and Watt W. Webb, is an outgrowth of confocal scanning microscopy...Read full article

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    Published: July 2003
    Glossary
    adaptive optics
    Adaptive optics (AO) is a technology used to improve the performance of optical systems by reducing the effects of atmospheric distortions. The Earth's atmosphere can cause light passing through it to experience distortions, resulting in image blurring and degradation in various optical applications, such as astronomical observations, laser communications, and imaging systems. Adaptive optics systems actively adjust the optical elements in real-time to compensate for these distortions. Key...
    astronomy
    The scientific observation of celestial radiation that has reached the vicinity of Earth, and the interpretation of these observations to determine the characteristics of the extraterrestrial bodies and phenomena that have emitted the radiation.
    adaptive opticsastronomyBasic ScienceBio-Rad Laboratoriesbiological imagingcommercialize multiphoton microscopy systemsFeaturesMicroscopy

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