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Blue light changes a fluorophore from green to red

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During the past several years, researchers have developed photoactivatable fluorescent proteins that are similar to GFP but that change color when introduced to UV-to-violet wavelengths. Unfortunately, UV radiation can be damaging to some of the biological entities one might wish to study. Now scientists at the Russian Academy of Sciences in Moscow have created a fluorescent protein, dubbed Dendra, that can convert from green to red with 1000 to 4500 times efficiency using a blue laser. A confocal image shows a cell with Dendra-tagged proteins concentrated in nucleoli. When...Read full article

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    Published: May 2006
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