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Bright, Photostable Dye Developed for In Vivo Voltage Imaging

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ASHBURN, Va., Aug. 12, 2019 — A “misfit” fluorescent dye, developed to round out a spectrum of dyes, is becoming a cornerstone of a new brain imaging tool developed at Howard Hughes Medical Institute’s Janelia Research Campus. The tool, which is named Voltron, lets researchers track neuron activity in living animals more precisely and for longer time periods than was once possible, the researchers said. Voltron is a modular system made from a dye molecule linked by a tag to an engineered, voltage-sensitive protein that is situated on the neurons’ membranes. Scientists can “form...Read full article

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