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Chemical Device Uses Light to Reprogram Gene Expression

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Researchers at Texas A&M have developed a chemical or light-inducible transcriptional reprogramming device to illuminate the functions of genes during different biological processes, using calcium and light. The CaRROT system (calcium-responsive transcriptional reprogramming tool) can control the transcription of genes within the body with a high degree of precision, including how, when, and where genes create the proteins that perform various cellular functions. The light-inducible device combines photoswitchable genetically encoded calcium actuators with dCas9 to control gene...Read full article

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