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Combined Imaging Techniques Promise Insights into MS

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WEST LAFAYETTE, Ind., April 18, 2007 -- By combining three types of microscopic imaging techniques that are ordinarily used individually, a way has been developed to analyze living tissue and learn more about the molecular mechanisms of multiple sclerosis, information that could help lead to earlier detection and new treatments. The combined imaging method is enabling the researchers to study how multiple sclerosis causes an overproduction of "astroglial filaments," which form bundles between critical nerve fibers and interfere with proper spinal cord functioning. The technique also promises to yield new information about how...Read full article

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    Published: April 2007
    Glossary
    coherent anti-stokes raman scattering
    A technique whereby two laser beams, one at an excitation wavelength and the second at a wavelength that produces Stokes Raman scattering, interact coherently in a sample, producing a strong scattered beam at the anti-Stokes wavelength.
    photonics
    The technology of generating and harnessing light and other forms of radiant energy whose quantum unit is the photon. The science includes light emission, transmission, deflection, amplification and detection by optical components and instruments, lasers and other light sources, fiber optics, electro-optical instrumentation, related hardware and electronics, and sophisticated systems. The range of applications of photonics extends from energy generation to detection to communications and...
    astroglialastroglial filamentsBasic ScienceBiophotonicsCARScellsChengcoherent anti-Stokes Raman scatteringImaginglipidMicroscopyMSmultiple sclerosismyelinNews & Featuresphotonicsspinal cordsum frequency generationtissuetwo-photon-excitation fluorescence

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