High-resolution, 3D multimodal imaging technology enables molecular, anatomical, and functional co-registration of features.MARK LITTLE PHOTOSOUND TECHNOLOGIES INC.The development of anticancer metastatic therapies for human clinical trials requires meticulous evaluation of efficacy and optimization of small animal test models in preclinical experimentation1. Critical information on morphology and the molecular microenvironment of tumors is currently obtained and monitored using noninvasive, in vivo imaging methods. 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