High-resolution, 3D multimodal imaging technology enables molecular, anatomical, and functional co-registration of features.MARK LITTLE PHOTOSOUND TECHNOLOGIES INC.The development of anticancer metastatic therapies for human clinical trials requires meticulous evaluation of efficacy and optimization of small animal test models in preclinical experimentation1. Critical information on morphology and the molecular microenvironment of tumors is currently obtained...Read full articleRelated content from Photonics MediaARTICLESBiomedical Photoacoustics Reverberates in ClinicsShortly before Alexander Graham Bell’s death in 1922, the Scottish American scientist and inventor said the telephone was not what he regarded as his greatest achievement. Rather, that...BioPhotonics October 2019 IssueThree-Photon Microscope Reveals Cortical Layers of Mouse BrainA new three-photon microscope developed at the Picower Institute at the Massachusetts Institute of Technology (MIT) can deliver rapid, short, low-power light pulses capable of reaching deep targets...BioPhotonics April 2019 IssueLOTUS-V Brain Imaging Technique Shows Promise In NeuroscienceResearchers at Osaka University have developed a method to record brain activity in multiple freely moving mice simultaneously. The method is based on a recent bioluminescence-based indicator of...BioPhotonics Jul/Aug 2019 IssueAntibody-based Probe Developed for Live-Cell Imaging in VivoTo expand the toolbox of imaging in living cells, researchers from Colorado State University and the Tokyo Institute of Technology have developed a genetically encoded, antibody-based probe that...BioPhotonics September 2019 IssuePRODUCTSAR/VR Lens: Measure Displays in HeadsetDisplays viewed near to the eye, such as those in AR/VR devices, create immersive virtual experiences. However, as display images are magnified to fill a user’s field of view, display defects...Promoted Content March 2018 IssueAR/VR Lens: Measure Displays in HeadsetDisplays viewed near to the eye, such as those in AR/VR devices, create immersive virtual experiences. However, as display images are magnified to fill a user’s field of view, display defects...Promoted Content September 2018 IssuePHOTONICS HANDBOOK ARTICLESDetectors: Options for Low-Light Applications: Silicon photomultipliers and photomultiplier tubes each boast unmatched sensitivity, yet their distinct characteristics make them suited for different uses.Developed in the early 1990s, the silicon photomultiplier (SiPM) is a solid-state photodetector whose sensitivity to light rivals that of a photomultiplier tube (PMT) in a regime where a few hundred...Photonics HandbookMachine Vision Cameras: Making the Right Selection: Improvements and affordability have broadened the use of vision systems for inspection, but several factors should be considered before making a purchase.Technological advances have resulted in new, higher-quality sensors that enable machine vision cameras to deliver greater features and functionality at a lower cost than ever before. These factors...Photonics HandbookMeasuring Small-Beam MFD: Overcoming the Challenges: Small beams are used in many critical applications yet often they are not directly profiled. While obtaining good beam profiling data on beams under 10 µm has its challenges, they can be overcome with proven techniques.Profiling beams under 10 µm in size is one of the more challenging beam profiling applications. There are numerous reasons for this, including the very small size. Focal plane arrays commonly...Photonics HandbookPolarization-Based Imaging: Basics and Benefits: With spatial correction, line scan polarization cameras detect birefringence, stress, surface roughness, and physical properties that cannot be detected with conventional imaging.There are three fundamental properties of light: intensity, wavelength, and polarization. Almost all cameras today are designed for monochrome or color imaging. A monochrome camera is used to measure...Photonics HandbookWHITEPAPERSAre Large Image Sensors A Perfect Fit for Large Field of View Microscope Applications?In the last years nearly all microscope manufacturers used image circles with 18 mm diameter to image their field of view to cameras connected to their microscopes. Only recently some microscope...Photonics.com 12/2/2019WEBINARSBiophotonic Imaging for Medicine: A Digital ConferenceResearchers from around the world presented their latest work at “Biophotonic Imaging for Medicine: A Digital Conference.” Presentations focused on a range of light-based imaging and...Photonics.com 6/11/2015Advances in Biomedical PhotonicsA Free Webinar: Advances in Biomedical Photonics, Thursday, July 19, at 1 p.m. EDT/10 a.m. PDT/ 5 p.m. GMT/UTC Questions & Answers from the Webinar: Lihong V. Wang, PhD Gene...Photonics.com 7/19/2012Techniques in Biophotonic ImagingFREE WEBINAR Sponsored by: Hamamatsu & Applied Scientific Instrumentation Additional Questions & Answers from the webinar are below: Dr. Kimani C. Toussaint Jr. Quantitative...Photonics.com 3/21/2013In Vivo Deep-Tissue Imaging with Optical Wavefront ControlOptical microscopy has become an indispensable tool in modern biology. The high spatial and temporal resolution and the rich molecular information offered by optical imaging have led to new...Photonics.com 5/27/2015PHOTONICS DICTIONARY TERMSspatial resolutionIn a vision system, the linear dimensions (X and Y) of the field of view, as measured in the image plane, divided by the number of pixels in the X and Y dimensions of the system's imaging array or...EDU.photonics.com 9/8/2009equatorial mountA telescope stand equipped with a polar axis that can be set parallel to the Earth's axis of rotation and a declination axis that is at right angles to the polar axis. If the telescope is turned at a...EDU.photonics.com 9/8/2009head-up display (HUD)An optical system that superimposes a synthetic display providing navigational or weapon-aiming information on a pilot's or driver's field of view. The system includes a cathode-ray tube, collimating...EDU.photonics.com 9/8/2009split fieldThe field of view seen through some types of coincidence rangefinders. It is formed by the juxtaposition of opposite halves of the images produced by two objectives, the half-images being separated...EDU.photonics.com 9/8/2009MEDIASkyscraper Fryers & Sculpted Light - LIGHT MATTERS 09.18.2013-Laser Bomb Detection -Sculpted Light -Skyscraper Fryer This week on Light Matters: a European group is working to taking the ‘fry’ out of ‘skyscrapers,’ sculpted light captures brain activity, and a...Photonics.com 9/18/2013PHOTONICS BUYERS' GUIDE CATEGORIESArea Image SensorsHead-Up DisplaysA head-up dispay is an optical system that superimposes a synthetic display providing navigational or weapon-aiming information on a pilot's or driver's field of view.Superresolution Imaging SystemsOptical Radars