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Diagnosis is in the eyes, thanks to color-coded markers

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Ashley N. Rice, [email protected]

New fluorescent probes that change color when they encounter brain disease markers found in the eye could offer a simpler way to identify neurodegenerative disease and distinguish between closely related disorders such as Parkinson’s, Alzheimer’s and Creutzfeldt-Jakob. Amyloids – sticky plaques of protein – mark several different but related brain diseases with overlapping symptoms. Methods for diagnosing and monitoring these disorders are not very advanced. Among the few available diagnostics for Alzheimer’s disease are radioactive molecules that...Read full article

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    Published: October 2012
    Glossary
    photonics
    The technology of generating and harnessing light and other forms of radiant energy whose quantum unit is the photon. The science includes light emission, transmission, deflection, amplification and detection by optical components and instruments, lasers and other light sources, fiber optics, electro-optical instrumentation, related hardware and electronics, and sophisticated systems. The range of applications of photonics extends from energy generation to detection to communications and...
    positron emission tomography
    A medical imaging device that uses a ring of crystal/photomultiplier tube assemblies encircling the patient to detect gamma rays emitted by positrons colliding with electrons.
    AlzheimersAmericasamyloidamyloid depositsamyloid proteinBasic SciencebiomarkersBiophotonicsBioScanbrain diseasebrain disease markersCaliforniaChristina SigurdsonCreutzfeld-JacobsEmmanuel Theodorakisfluorescent markersfluorescent probesindustrialJerry Yangneurodegenerative disease diagnosisNewsParkinson’sPET scanphotonicspositron emission tomographyTest & MeasurementUniversity of California San Diego

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