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Dynamic Light-Scattering Method Could Guide Alzheimer’s Diagnosis and Treatment

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By spectroscopically measuring temporal fluctuations of scattered light, clinicians can predict the progression of diseases that manifest in molecular changes in the eyes.

JEFFREY N. WEISS, MICRON OPHTHALMIC INC.

The early detection of neurologic damage caused by Alzheimer’s disease, before symptoms have appeared, is integral to the development of effective treatments. Early detection, made possible by leveraging dynamic light scattering to identify subtle cellular changes, could facilitate intervention that might prevent progression of the disease. It could even help plot a successful treatment. This technology could not only offer data leading to an early diagnosis of the condition but also help determine drug efficacy at an earlier stage of the disease. And beginning a regimen as soon as...Read full article

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    BioPhotonics
    Mar/Apr 2023
    GLOSSARY
    brownian motion
    The behavior of microscopic solid particles suspended in a fluid, first observed by botanist Robert Brown in 1827 as a continuous random motion.
    Featuresdynamic light scatteringAlzheimer’s diseasebeta-amyloid plaquestau tanglesretinal nerve fiberdrug studiesBrownian motionanisotropyscattered light intensity

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