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Hamamatsu Corp. - Earth Innovations LB 2/24

Flourescence Microscope Helps Solve DNA Mystery

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CHAMPAIGN, Ill., Oct. 22 -- Using an optical fluorescence microscope to monitor enzyme activity, researchers at three universities have solved a long-running mystery: It takes at least two proteins, working in an unstable tandem, to unzip two strands of DNA. Their new approach, which focuses on the activity of single molecules, also showed for the first time that if one protein falls away, the process stops. Unless another climbs aboard, DNA reverts to its zipped state. The technique, which offers a new way to study activities of many other proteins in general, and the new findings...Read full article

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    Published: October 2002
    MicroscopyNews & Features

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