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Fluorescent DNA Could Detect Cancer Early, UF & Columbia Researchers Say

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GAINESVILLE, Fla., & NEW YORK, Nov. 30 —- University of Florida and Columbia University researchers say they are a step closer to a technique to easily detect a wide variety of cancers before symptoms become apparent. The findings involve introducing molecularly engineered strands of DNA into cell cultures and observing whether they unleash a fluorescent burst after they adhere to cancer proteins. The technique could enable doctors to search within extremely complex fluid or tissue samples to pinpoint biomarkers -— proteins that signal that something is wrong. “Even when the cancer...Read full article

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    Published: November 2005
    Glossary
    cell
    1. A single unit in a device for changing radiant energy to electrical energy or for controlling current flow in a circuit. 2. A single unit in a device whose resistance varies with radiant energy. 3. A single unit of a battery, primary or secondary, for converting chemical energy into electrical energy. 4. A simple unit of storage in a computer. 5. A limited region of space. 6. Part of a lens barrel holding one or more lenses.
    fluorescence
    Fluorescence is a type of luminescence, which is the emission of light by a substance that has absorbed light or other electromagnetic radiation. Specifically, fluorescence involves the absorption of light at one wavelength and the subsequent re-emission of light at a longer wavelength. The emitted light occurs almost instantaneously and ceases when the excitation light source is removed. Key characteristics of fluorescence include: Excitation and emission wavelengths: Fluorescent materials...
    assayBasic SciencebiodetectioncancerCellColumbiaDNAfluorescencemoleculesNews & FeaturesPDGFPrasadproteinTanUniversity of FloridaWeihongYang

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