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Fluorophore Modified to Expand Monitoring of Cell Dynamics

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A genetically modified fluorescent protein has exhibited the shortest fluorescence emission wavelength to date, researchers at Osaka University reported. The fluorophore, named Sumire, emits 414-nm violet fluorescence from a hydrated chromophore. The development of Sumire will make it possible for scientists to track a larger number of biomolecules at the same time, increasing their ability to simultaneously monitor a cell’s many dynamic processes. Chromophore structure of short wavelength side Aequorea victoria green fluorescent protein (avGFP) mutants. Courtesy of Kazunori Sugiura....Read full article

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    Published: November 2022
    Glossary
    fluorescence
    Fluorescence is a type of luminescence, which is the emission of light by a substance that has absorbed light or other electromagnetic radiation. Specifically, fluorescence involves the absorption of light at one wavelength and the subsequent re-emission of light at a longer wavelength. The emitted light occurs almost instantaneously and ceases when the excitation light source is removed. Key characteristics of fluorescence include: Excitation and emission wavelengths: Fluorescent materials...
    fluorophore
    A fluorophore is a molecule or a portion of a molecule that has the ability to emit light upon excitation by an external energy source, such as ultraviolet or visible light. The process by which a fluorophore absorbs and then re-emits light is known as fluorescence. Fluorophores are widely used in various scientific and technological applications, including fluorescence microscopy, flow cytometry, medical imaging, and molecular biology. Key features of fluorophores include: Excitation and...
    Research & TechnologyeducationAsia-PacificOsaka Universityfluorescent tagsfluorescencefluorescent proteinsImagingLight SourcesMicroscopyOpticsBiophotonicsmedicalgenetic engineeringfluorophorefluorophoresBioScan

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