Dr. Stuart Yin, Pennsylvania State UniversityHigh-speed, multichannel fluorescence confocal imaging can be achieved by encoding the spatial location information into the frequency domain. Fluorescence confocal microscopy is an important tool for studying live biological cells, and it can reject out-of-focus fluorescence so that an image with a high signal-to-noise ratio can be obtained over the scattering biomedical media. To understand cellular systems, it is necessary to observe fast biological processes — such as cardiac myocyte contraction — in real time. Multichannel methods can increase imaging speed; however,...Read full articleRelated content from Photonics MediaARTICLESMiniaturization in NIR Spectroscopy Reshapes Chemical AnalysisNear-infrared (NIR) spectroscopy has been used in groundbreaking research in many of the life sciences1 due to its capacity to rapidly determine and analyze the composition of materials. Bulky...BioPhotonics Jan/Feb 2022 IssueCamera Selection for Low-Light ImagingFluorescence microscopy is a broadly used term, with applications ranging from basic life science, such as time-lapse cell viability assays, to sophisticated techniques in which a very few photons or...Photonics Spectra June 2021 IssueSingle-Photon Avalanche Diodes Sharpen Spatial and Temporal ResolutionAs their name implies, single-photon avalanche diodes (SPADs) detect single particles of light, and they do so with picosecond precision. Single-pixel SPADs have found wide use in astronomy, flow...Photonics Spectra May 2022 IssueMicroscopy Technique Enhances 3D Imaging CapabilityOptical microscopes use light to visualize detailed structures of small samples. The most popular microscopy technique for biological or biomedical studies by far is wide-field microscopy, in which a...BioPhotonics Mar/Apr 2021 IssuePRODUCTSRack Decoding SoftwareThe DP5 Network 2D rack decoding web browser software from Ziath Ltd. enables full control of multiple tube barcode scanners on the same local area network to be operated from one or more devices. ...Photonics.com 11/3/2021Microscopy Staining KitsExoBrite™ EV Membrane Staining Kits from Biotium Inc. are designed for fluorescent staining of exosomes or extracellular vesicles with little to no background. The kits provide an...BioPhotonics Nov/Dec 2021 IssueSensor ModuleThe FSM-IMX678 sensor module from FRAMOS GmbH features the Sony IMX678 CMOS image sensor and can be used for testing and validation solutions in medicine, microscopy, augmented reality, security,...Photonics Spectra May 2022 IssueBack Illuminated CameraThe pco.edge 10 bi CLHS sCMOS back illuminated camera from PCO features high resolution and low noise at a high frame rate, making it ideal for life science applications like high content screening,...Photonics.com 10/5/2021PHOTONICS HANDBOOK ARTICLESInfrared Spectral Selection: It Begins with the Detector: An IR imaging system employing a narrow spectral band brings hidden images to light, broadening IR imaging’s applications.Spectral selection is a powerful tool that enhances conventional imaging tremendously. Most imaging systems, including the human eye, are designed to image light over a broad range of the spectrum....Photonics HandbookMicroscopy Illumination: Considering Nonlaser Light Sources: Metal halide and LED light sources are changing the illumination landscape in microscopy. Brighter, easier to use and growing in application, they are driving new options in fluorescence, conventional bright-field and other contrast techniques.As recently as five years ago, shopping for a microscope light source was fairly straightforward. For routine applications, it was tungsten halogen, typically 100 W, while for fluorescence, it was an...Photonics HandbookLasers for Microscopy: Major Trends: In order for biologists, drug developers, clinical lab professionals and other scientists to fully exploit new microscopy techniques and applications, parallel developments in laser technology are often required. Laser manufacturers are responding with products optimized to match the needs of these applications.Laser development for the microscopy market continues to be driven by key trends in applications, which currently include superresolution techniques, multiphoton applications in optogenetics and...Photonics HandbookPhotonic Component Manufacturing: Moving Toward Automation: A shift in assembly methods would help reduce costs and increase production in the optoelectronics manufacturing and packaging industries.Manufacturing the laser diode is complicated by the existence of multiple proprietary techniques and intellectual property barriers together with complex device physics and unique materials. ...Photonics HandbookWHITEPAPERSRecent Research Using Meadowlark Optics Spatial Light ModulatorsThis ever-evolving collection of recent research using Meadowlark Optics Spatial Light Modulators offers a brief overview of specific applications in which Meadowlark Optics’ Spatial Light Modulators...Photonics.com 9/4/2020A Comparison of Some of the Key Technologies and Characteristics in CCD and CMOS SensorsTo assist in choosing the right technology for an application, this paper covers: • Historical background • Architecture • Improvements • Binning • Fill factor • Full well depth and capacity •...Photonics.com 2/16/2022Using Imaging Colorimeters to Correct OLED, MicroLED, and Other Emissive Displays for Production Efficiency and YieldsImaging colorimeters can improve OLED and microLED display production by ensuring visual quality of displays — measuring brightness and color uniformity at the pixel and subpixel level to correct...Photonics.com 1/14/2021High-Speed Imaging in Biomedical Microfluidic ResearchThis whitepaper discusses multiple case studies when Phantom cameras have assisted in the advancement of microfluidic and cellular research.Photonics.com 11/17/2020WEBINARSWavelength-Selective Optical Filters: Providing More Signal and Less Background to PCR InstrumentsEngineers face many unique challenges when creating polymerase chain reaction (PCR) instrumentation. These challenges are seen in both the qualitative detection of nucleic acid sequences, using...Photonics.com 7/7/2022Micro-Spectroscopy: Enabling Research From Novel Nano-Devices To Clinical DiagnosisMicro-spectroscopy is an ever developing modality for new and exciting research in the areas of nano-technology and bioscience. This webinar will look at modular approaches to microspectroscopy and...Photonics.com 3/24/2015Simplifying Fluorescence Microscopy Using Next-Generation Laser TechnologyKonstantin Birngruber and Max Eisele introduce TOPTICA's next-generation laser technology by highlighting multicolor light engines for standard fluorescence microscopy, as well as TOPTICA's...Photonics.com 10/26/2021Toward Intelligent Microscopes: Deep Learning's Potential for Biomedical ApplicationsDeep learning is a class of machine learning techniques that use multilayered artificial neural networks for automated analysis of signals or data. The name comes from the general structure of deep...Photonics.com 1/22/2021PHOTONICS DICTIONARY TERMSflying spot microscopeA microscope that uses a flying spot scanner, directed through the eyepiece, as a light source to determine the features of a transparent specimen. The flying spot is modulated by the varying density...EDU.photonics.com 9/8/2009spectrometer maskA high-contrast transparency of the gas sought, or an array of exit slits that correlates with some features of the spectrum. No standardized formula for positioning, number or thickness has been...EDU.photonics.com 9/8/2009backlightingThe forming of a clear silhouette of an object by placing a light source behind it. Used in machine vision when surface features of an object are not important.EDU.photonics.com 9/8/2009convolutional neural networkA powerful and flexible machine-learning approach that can be used in machine vision to help solve difficult problems. Inspired by biological processes, multiple layers of neurons process portions of...EDU.photonics.com 6/30/2017MEDIAPhotonics on the Showroom Floor and in the Lab - LIGHT MATTERS 02.2018On this month's episode of Light Matters, we take you on a brief tour of the Higgins Laboratories at Worcester Polytechnic Institute (WPI). Quinsigamond Community College and WPI received a $4M grant...Photonics.com 2/21/2018Fundamentally Different Photonics - LIGHT MATTERS 03.2018On this month's episode of Light Matters, we take you to the South by Southwest (SXSW) Trade Show in Austin, Texas, as new photonics innovations hit the show floor of the Austin Convention Center....Photonics.com 3/29/2018Light Matters Extra: Weird and Strange: Quantum Photonics - 03.2018In this month's Light Matters Extra, we take you to the Quantum Photonics Laboratory at MIT run by Dr. Dirk Englund. Dr. Englund's group, the Quantum Photonics Group, is made up of postdocs and...Photonics.com 3/29/2018Welcome to CoolLEDIntroducing the experts who design and manufacture high performance LED Illumination Systems.Photonics.com 1/24/2022PHOTONICS BUYERS' GUIDE CATEGORIESMedical/Biomedical Light SourcesPicosecond LasersSupercontinuum LasersOptical RadarsCOMPANIESOZ Optics LimitedEstablished in 1985, OZ Optics is a leading worldwide supplier of fiber optic components, test equipment and sensors. OZ Optics manufactures its products in three locations, Ottawa (Canada),...Photonics Buyers' GuideAndor TechnologyWe are global leaders in the development and manufacture of high performance scientific digital cameras for academic, industrial and government applications. Through continuous dialogue with our...Photonics Buyers' GuideLaCroix Precision OpticsOptics that Defend, Build, Cure and Discover The LaCroix name is synonymous with quality precision optics. Since 1947, three generations of family leadership have placed LaCroix Precision Optics...Photonics Buyers' GuideMad City Labs Inc.Mad City Labs, Inc. is a leading manufacturer of piezo nanopositioning systems and instrumentation capable of sub-nanometer positioning resolution. Our product line of nanopositioners,...Photonics Buyers' Guide