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Deposition Sciences Inc. - Difficult Coatings - LB - 8/23

GFP trapped in a nanodrop

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Researchers at the National Institute of Standards and Technology in Gaithersburg, Md., have developed a technique to contain single protein molecules within optically trappable aqueous nanodroplets. The method is minimally destructive to the protein, and it offers an alternative to surface attachment or lipid encapsulation. The scientists developed a piezoelectric actuated micropipette that inertially injected individual nanodroplets containing enhanced GFP into an immiscible perfluorotriamylamine matrix. Each droplet produced had a diameter of ≥700 nm. The drops could be optically...Read full article

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    Published: April 2008
    Glossary
    fluorescence
    Fluorescence is a type of luminescence, which is the emission of light by a substance that has absorbed light or other electromagnetic radiation. Specifically, fluorescence involves the absorption of light at one wavelength and the subsequent re-emission of light at a longer wavelength. The emitted light occurs almost instantaneously and ceases when the excitation light source is removed. Key characteristics of fluorescence include: Excitation and emission wavelengths: Fluorescent materials...
    As We Go To PressBiophotonicsBreaking NewsenergyfluorescenceMicroscopypiezoelectric actuated micropipettePresstime Bulletinsingle protein molecules

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