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Ghent Researchers, SERS, Perform and Demonstrate Sensitive Protease Monitoring

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GHENT, Belgium, Sept. 11, 2020 — Researchers at Ghent University have detected protease using surface-enhanced Raman spectroscopy (SERS) performed with a tiny waveguide. The work moves toward real-time, label-free, lab-on-a-chip protease monitoring, which could offer a high-throughput approach to screen for new drugs that inhibit proteases involved in disease. Proteases, which break down the peptide bonds that hold proteins together, play an important role as drug targets due to their functionality in diseases such as cancer, Alzheimer’s disease, and arthritis. “We hope that our interdisciplinary approach can...Read full article

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