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High-Speed Imaging for DNA Sequencing

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EMCCD technology aids sequencing technique.

Dr. George M. Church, Dr. Gregory J. Porreca, Richard C. Terry, Harvard Medical School, and Maridel Lares, Hamamatsu Corp.

The key to personalized medicine is understanding the role that an individual’s genes play in his or her health. To reap the benefits of personalized medicine, the billions of nucleotide bases that comprise an individual’s genome must be sequenced — and done so at an affordable price. This means lowering the price tag from the $3 billion spent on the Human Genome Project to $100,000 and, eventually, to $1000. Reaching this goal will require a fundamentally different approach to DNA sequencing that delivers significantly more bases of accurate sequence per dollar than do current sequencers....Read full article

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