BERKELEY, Calif., March 23, 2020 — University of California, Berkeley, researchers have built a microscope that can image the brain of an alert mouse 1000 times a second and record the passage of millisecond electrical pulses through neurons. The new imaging technique combines two-photon fluorescence microscopy and all-optical laser scanning in a microscope that can image a 2D slice through the neocortex of the mouse brain up to 3000 times per second. According to the researchers, that’s fast enough to trace electrical signals flowing through brain circuits. 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