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Lasers, Optics Enhance Optogenetics Studies

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Niten Olofsson, Iakovos Lazaridis, Konstantinos Meletis and Marie Carlén, Karolinska Institutet, and Ulf Tingström and Håkan Karlsson, Cobolt SE

A guide to suitable light sources and fiber optic components for optogenetics research, with a specific emphasis on rodent behavior. The use of lasers and optics for optogenetics is only in its infancy. In the next decade, we can expect researchers to uncover many inner secrets of the human brain and possibly also find cures and treatments for some of our most challenging psychiatric disorders and diseases, helping us to a better life. Optogenetics builds on the discovery that light-activated molecules called opsins can be expressed in neurons (Figure 1). Light-sensitive neurons...Read full article

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