JOEL WILLIAMS, ASSOCIATE EDITOR [email protected]A fluorescence microscope being developed by imec researchers will be able to achieve high throughput and high resolution, without a lens component. The technology could significantly speed up next-generation DNA sequencing and cellular research, as well as enable studies on larger scales. Part of the trouble that researchers face with ordinary fluorescence microscopes, said Niels Verellen, principal scientist at imec, stems from certain limitations of lenses. As magnification increases, throughput — or field of view — decreases. The light field's interference patterns...Read full articleRelated content from Photonics MediaArticlesModule Uses Single-photon Microscopy to Track Cellular ActivityBrightEyes-TTM, an open-source time-tagging module (TTM) developed at the Italian Institute of Technology (IIT), enables scientists to observe the dynamic processes of molecules inside living cells...BioPhotonics May/Jun 2023 IssueAlgorithm Boosts Live-Cell Imaging's CapabilitiesSuperresolution radial fluctuations (SRRF), a superresolution algorithm, works by observing fluctuations in radial symmetry throughout the frames of an image. SRRF supports live-cell, superresolution...Photonics Spectra February 2024 IssueHigh-Throughput Imaging Links Microbial Metabolism With Cell IdentityAn imaging platform for investigating microbiomes in medical and environmental samples can perform high-throughput metabolism and identity analyses with single-cell resolution. Called SRS-FISH, or...BioPhotonics Sep/Oct 2022 IssueMicroscopy Method Uses Infrared Light to Image Molecules with Vibrational ContrastThe complementary strengths of fluorescence and vibrational microscopy are combined in a new technique developed at Caltech, which is called bond-selective fluorescence-detected infrared-excited...BioPhotonics Sep/Oct 2023 IssueProductsFLIM Camera SystemThe LIFA vTAU from Lambert Instruments is a camera-based system designed to transform fluorescence lifetime imaging microscopy (FLIM) for live cell applications. Featuring a single-photon avalanche...BioPhotonics Nov/Dec 2023 IssuesCMOS CameraThe ZL41 Cell sCMOS camera from Andor Technology is designed for life science researchers. The ZL41 Cell transforms a normal fluorescence microscope into a super-resolution microscope using...BioPhotonics Jan/Feb 2023 IssuesCMOS CameraThe Sona-6 back-illuminated sCMOS camera from Andor Technology can be used for life science research and detection in challenging, light-starved imaging applications. The noise floor has been...Photonics.com 11/16/2022USB3 CamerasSix construction variants and numerous CMOS sensors in the CP and LE camera series can be chosen for IDS Imaging Development Systems GmbH’s uEye+ product line of USB3 cameras. Suitable...Photonics.com 10/7/2022Photonics Handbook ArticlesFluorescence Lifetime Imaging: Choosing the Best ApproachThe term fluorescence is often applied as a synonym for photoluminescence, although luminescence actually covers fluorescence and phosphorescence. Both of these terms describe the process of...Photonics HandbookRadiation Tolerances: Effects on CID Imaging DevicesLike other CTDs, the CID imager uses hundreds of thousands (up to 4 million) pixel elements to capture optical images, and converts the light into an electronic charge which may be displayed on a...Photonics HandbookInfrared Spectral Selection: It Begins with the DetectorSpectral selection is a powerful tool that enhances conventional imaging tremendously. Most imaging systems, including the human eye, are designed to image light over a broad range of the spectrum....Photonics HandbookAspheric Lenses: Design ConsiderationsAspheric surfaces are powerful tools that combine the optical corrections of multiple lenses into a single element (Figure 1) and affect performance in ways that spherical optics cannot. For example,...Photonics HandbookWhite PapersSingle-Objective Light SheetAn overview of the Single-Objective Light Sheet.Photonics.com 1/10/2024Multi-Bandpass Filters for FluorescenceLearn how multi-bandpass filters combined with multiple LEDs can enable versatile and compact fluorescence instrumentation.Photonics.com 2/28/2024Raman SpectroscopyTo achieve accurate and precise Raman measurements, optical filters play a crucial role in enhancing signal-to-noise ratio, and reducing background interference. This white paper explores the...Photonics.com 9/27/2023Cricket 2 Single MCPAdvanced Image Intensifier adapter for low light level imaging applications, the Cricket™² is a plug & play camera attachment enabling low light level imaging and extreme high shutter speeds for CMOS...Photonics.com 10/11/2022WebinarsBioPhotonics Conference: October 26 - 28The publishers of BioPhotonics invite you to attend a free virtual conference spanning three days. The BioPhotonics Conference will feature insights and innovations in microscopy, spectroscopy, flow...Photonics.com 10/26/2021Computational Microscopy, Sensing and Diagnostics for Telemedicine and Global Health ApplicationsAdditional Questions and Answers from the Webinar are below: With more than 6 billion cell phone users in the world, the majority of them in developing countries, there are opportunities for...Photonics.com 6/5/2013European Photonics Manufacturing Services Funded by ECThis event is supported by the European initiatives presented and is moderated by EPIC, the European Photonics Industry Consortium. The European Commission is helping companies access the...Photonics.com 6/30/2021Biophotonic Imaging for Medicine: A Digital ConferenceResearchers from around the world presented their latest work at “Biophotonic Imaging for Medicine: A Digital Conference.” Presentations focused on a range of light-based imaging and...Photonics.com 6/11/2015Photonics Dictionary Termsfreeform mirrorsFreeform mirrors refer to reflective optical components that deviate from traditional symmetric or rotationally symmetric shapes, such as spheres or paraboloids. Unlike conventional mirrors, which...Photonics Dictionaryspatially offset Raman spectroscopySpatially offset Raman spectroscopy (SORS) is a technique that extends traditional Raman spectroscopy by incorporating measurements at different spatial offsets. This method allows for the selective...Photonics Dictionarylinear opticsLinear optics refers to the study and manipulation of light in a linear and deterministic manner, where the response of optical elements is proportional to the amplitude of the incident light wave....Photonics Dictionarymicrolens arrayA microlens array is a grid-like structure composed of numerous small lenses, typically arranged in a regular pattern. Each individual lens in the array is referred to as a microlens. These...Photonics DictionaryMediaNew ZL41 Cell & Sona sCMOS - Easy, Flexible, Cost-Effective Super Resolution Microscopy - Andor TechnologyEasy and Cost-Effective Super-Resolution to ~100 nm. Andor has introduced two new highly innovative sCMOS cameras, both delivering easy and cost-effective access to super-resolution capabilities and...Photonics.com 11/20/2023Photonics on the Showroom Floor and in the Lab - LIGHT MATTERS 02.2018On this month's episode of Light Matters, we take you on a brief tour of the Higgins Laboratories at Worcester Polytechnic Institute (WPI). Quinsigamond Community College and WPI received a $4M grant...Photonics.com 2/21/2018Silicon Photon Emitter & Lens-Free Microscopy - LIGHT MATTERS 12.24.2014On this week's show we’ll learn about a lens-free microscope that could be just as useful as its optical counterparts for pathology. But first we’ll bring you December’s top business news, introduce...Photonics.com 12/24/2014New Dragonfly 600 Confocal Microscope System - Andor TechnologyThe Dragonfly 600 confocal microscope system delivers outstanding multi-dimensional images from subcellular (nm) to whole organism (cm), while significantly boosting productivity. Its unrivalled...Photonics.com 11/20/2023Photonics Buyers' Guide CategoriessCMOS Image SensorsCMOS Image SensorsA CMOS image sensor is a type of semiconductor device used to capture visual information and convert it into electrical signals for digital imaging applications. CMOS image sensors are widely...Fluorescence MicroscopesToolmaker MicroscopesCompaniesAndor TechnologyAndor Technology Ltd is a global developer and manufacturer of high-performance scientific cameras, microscopy systems and spectrographs for academic, government, and industrial applications. Founded...Photonics Buyers' GuideOZ Optics LimitedEstablished in 1985, OZ Optics is a leading worldwide supplier of fiber optic components, test equipment and sensors. OZ Optics manufactures its products in three locations, Ottawa (Canada),...Photonics Buyers' GuideBAE Systems Sensor SolutionsExpanding upon the storied Fairchild Imaging legacy, we offer a wide range of imaging devices that provide our customers with top performance and key features for the most demanding applications. Our...Photonics Buyers' GuideBaumer Ltd.Baumer Group is a manufacturer of sensors, encoders, measuring instruments, and components for automated image processing. Baumer combines innovative technologies and customer-oriented service into...Photonics Buyers' Guide