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Licensing Agreement

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The University of California, San Francisco, has given Carl Zeiss MicroImaging GmbH license to commercialize a superresolution microscopy technique developed by scientists at the university. Called structured illumination microscopy, the technique combines a special illumination pattern with state-of-the-art computational image analysis. Compared with conventional microscopes, its resulting superresolution images have up to double the resolution in all three spatial directions. The agreement grants the company the right to integrate the technique into its microscope systems.Read full article

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    Published: March 2010
    Glossary
    illumination
    The general term for the application of light to a subject. It should not be used in place of the specific quantity illuminance.
    microscope
    An instrument consisting essentially of a tube 160 mm long, with an objective lens at the distant end and an eyepiece at the near end. The objective forms a real aerial image of the object in the focal plane of the eyepiece where it is observed by the eye. The overall magnifying power is equal to the linear magnification of the objective multiplied by the magnifying power of the eyepiece. The eyepiece can be replaced by a film to photograph the primary image, or a positive or negative relay...
    superresolution
    Superresolution refers to the enhancement or improvement of the spatial resolution beyond the conventional limits imposed by the diffraction of light. In the context of imaging, it is a set of techniques and algorithms that aim to achieve higher resolution images than what is traditionally possible using standard imaging systems. In conventional optical microscopy, the resolution is limited by the diffraction of light, a phenomenon described by Ernst Abbe's diffraction limit. This limit sets a...
    BusinessCarl Zeiss MicroImaging GmbHcomputational image analysisilluminationlight speedmicroscopeMicroscopyOpticsSan Franciscospatial directionstructure illumination microscopysuperresolutionsuperresolution microscopyUniversity of California

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